The Library of Congress holds many collections relevant to the study of the Holocaust. Researchers, genealogists, and historians will find a wealth of resources in the Manuscript Reading Room that cover the history of the Holocaust in Europe, the Jewish experience, testimonies, American foreign policy before and after the Second World War, and related American journalist experiences abroad, including site visits to various camps and ghettos. This guide includes search tips, suggested collections, and provides access to selected Library of Congress Digital Collections, as well as outside resources pertaining to Holocaust studies.

The Manuscript Division primarily collects materials related to the United States and American political, cultural, and social events, movements, and persons. There are also significant foreign holdings in the division's custody. Only the official records of the State Department surpass the richness of the Manuscript Division's holdings for documenting American foreign policy. Researchers will find many relevant materials when searching the papers of secretaries of state and foreign ambassadors, anthropologists, scholars, and scientists. The papers of journalists and psychoanalysts also offer many records and files that concern Nazi war crimes, Holocaust survivors, and concentration camps across Europe.