The Library of Congress Manuscript Division houses the papers of most U.S. presidents from George Washington through Calvin Coolidge. All collections of presidential papers after Coolidge are held at the National Archives and Records Administration as part of their presidential libraries program.

The following collection titles link to fuller bibliographic information in the Library of Congress Online Catalog. Links to additional online content, including finding aids for the collections and digital collections, are included when available. Collections not available online are available on microfilm. Many institutions own copies of the microfilm collections, and copies are also available for use in the Manuscript Reading Room. The papers of John Adams and John Quincy Adams, Rutherford B. Hayes, and Warren G. Harding are not in the custody of the Manuscript Division, but microfilm editions of these collections are available in the Manuscript Reading Room.

Most presidential collections include an index to correspondence, which may be found under "Expert Resources" for the digital collections and in the bibliographic descriptions and catalog records.